The head of Bolivia's state energy company Santos Ramirez told about the incident on Wednesday.
Activists opposed to President Evo Morales are being blamed for the explosion.
The energy company says protesters took over an energy plant and closed a valve, creating pressure that blew up the pipeline, said an Associated Press report.
Ramirez said the action has reduced by 3 million the 30 million cubic metres of gas Bolivia sends Brazil each day. He called it a "terrorist threat."
Repairs to the pipeline will cost $100 million and take about 20 days, said a Bloomberg report.
Anti-government protesters have also trashed public offices and blocked roads in their attempt to keep more of Bolivia's energy resources for the nation's richer
provinces.
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A pipeline Explosion in Bolivia
A gas line exploded in Tarija state causing natural gas exports cut to Brazil by 10%